Plot options

 

Use multiple genes

Use list of genes Use mean expression of selected genes
Use ratio of two genes Filter by median expression
more genes param

Example

Example input for multiple genes:
1007_s_at 1
200000_s_at -1
31637_s_at 0.5
40016_g_at -2

Explanation:
first: normal,
second: gene is inverted,
third: gene has weight,
fourth: gene has weight and is inverted

You can also use following format:
1007_s_at, 1
200000_s_at, -1
31637_s_at, 0.5
40016_g_at, -2

Split patients by
Auto select best cutoff INFO
Trichotomization :  INFO
 INFO
INFO INFO

Restrict analysis to subtypes...

Anti-PD-1 treatment: (n=520)
Anti-PD-L1 treatment: (n=486)
Anti-CTLA-4 treatment: (n=121)
Sample acquisition:

Restrict analysis to clinical cohorts...

Tumor type:
Gender: (n=1069)

Please note: the generated p value does not include correction for multiple hypothesis testing by default.

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Please kindly cite our paper to support further development: Kovacs SA, Fekete JT, Gyorffy B: Predictive biomarkers of immunotherapy response with pharmacological applications in solid tumors, Acta Pharmacol Sin. 2023 Apr 13. doi: 10.1038/s41401-023-01079-6.

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